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Investigations • Hb metoclopramide 10 mg overnight delivery gastritis diet and treatment, Urinalysis • Plain abdominal X−ray may be useful in calcified tumours and some dermoid cysts • Ultrasound where facilities exist generic metoclopramide 10mg with visa gastritis zeluca. Management • Cysts greater than 8 cm need laparotomy • Cystectomy or salpingo−oophorectomy and histology purchase metoclopramide 10mg mastercard gastritis diet 8 jam. Secondary amenorrhoea refers to cessation of the periods after menstruation has been established generic 10 mg metoclopramide viral gastritis diet. Commonest variety seen is imperforate hymen occurring at menarche (12−14 years) with cyclic abdominal pains. Management • Admit to hospital for cruciate incision, which is a cure for imperforate hymen. A good menstrual history and physical examination is sufficient: a pregnancy test or ultrasound are sufficient to diagnose early pregnancies • In the pathological type investigations focus on uterine lesions, ovarian lesions, pituitary disorders, other endocrine disorders, psychiatric illness or emotional stress and severe general illness. Primary amenorrhoea is investigated after age 18 and secondary amenorrhoea at any age when 6 or more cycles are missed. Metrorrhagia refers to irregular uterine bleeding independent of or in between regular periods. Dysfunctional Uterine Bleeding refers to those cases in which the bleeding is neither due to some obvious local disorder, such as pelvic infection or new growth, nor to some complication of pregnancy. Metropathia haemorrhagica describes periods of amenorrhoea of 6−12 weeks followed by prolonged spotting 2−4 weeks and on curettage and histology there is cystic glandular hyperplasia. Clinical Features • Irregular periods associated with anovulation are commonest at puberty and perimenopause and at some stage during reproductive years, (14−44 years). Management • At puberty re−assurance may suffice 209 • Irregular periods with associated anovulation need hormonal therapy at any age. Accompanied by nervous irritability, depression, headache, listlessness and discomfort in breasts. Investigations • Speculum examination shows easily bleeding lesion on the cervix • Hb • Biopsy. Differential diagnosis include: Granuloma inguinale, lymphogranuloma venereum, syphilitic chancre or gummata and chancroid. Management • Suspicious lesions should be referred to gynaecologist • Treatment is by surgery (Radical vulvectomy) • Extent of surgery will depend on the primary tumour • Radiotherapy and chemotherapy and surgery for advanced disease. Clinical Features Post coital bleeding, dyspareunia, watery discharge, urinary frequency or urgency or painful defecation. Management • Depends on location and extent of the disease 213 • A tumour localised in the upper 1/3 of the vagina is treated either by radical hysterectomy with upper vaginectomy and pelvic lymph node dissection or with radium and external radiotherapy • Treatment of secondary carcinomas and 1 ° carcinoma is usually combined and may be either radiotherapy or radical surgery. Gonorrhoea and Chlamydia trachomatis principally results in endosalpingitis whereas puerperal and post−abortion sepsis result in exosalpingitis. If fever persists after 48−72 hrs of antibiotic cover, perform vaginal examination. If there is pelvic collection (bulge in pouch of Douglas) and/or adnexal masses − pelvic abscess is suspected and laparotomy for drainage done. At laparotomy, drainage, peritoneal toilet with warm saline and leave drain in situ for about 3 days and continue parenteral antibiotics post−operatively. Clinical Features Patient may complain of any combination of symptoms: Local pain, low−grade fever, perineal discomfort, labial swelling, dyspareunia, purulent discharge, difficulty in sitting. Physical examination may reveal; tender, fluctuant abscess lateral to and near the posterior fourchette, local swelling, erythema, labial oedema, painful inguinal adenopathy. Most abscesses develop over 2−3 days and spontaneous rupture often occurs within 72 hours. Instrumental delivery may cause perforation of the vagina and rectum; Operative injury A fistula may be caused during total abdominal hysterectomy and Caesarian section; Extension of Disease Malignancy of the bowel or any pelvic abscess may perforate into the rectum and posterior vaginal wall; Radiotherapy Heavy radiation of the pelvis causes ischaemic necrosis of the bladder wall and bowel causing urinary or faecal fistula. Refer If • Diagnosis is confirmed after examination • Reconstructive surgery is deferred 3 months after the initial injury or after a previous attempt at repair to allow− all tissue reaction to subside. Under Kenyan laws rape is defined as carnal knowledge of a woman without her consent or by use of force, duress or pretence. A girl 216 below 14 years of age in Kenya is not legally deemed to be able to give consent. Clinical Features These will range from none or mild to very severe injuries that may be life threatening. The medical personnel must approach the rape victim with great understanding, respect and concern for her well being. Careful history and medical record is important because this will be required in court. If the patient has eaten, drunk, bathed or douched, this may affect the outcome of laboratory test. History must be taken to evaluate the risk of acquisition of sexually transmitted disease and pregnancy. During physical examination, document location, nature and extent of external trauma to face, neck, breast, trunk, limbs, the genitalia, vagina and cervical trauma must also be documented. Management • All cases should be reported to the police • Treat physical injuries that may require surgical repair of tears • Tetanus toxoid for soiled lacerations • Give prophylactic treatment to prevent pregnancy after ruling out already existing pregnancy. Eugynon or Neogynon • Give prophylactics against sexually transmitted disease [see 2. It should include age, marital status, occupation, education, ethnic origin, area of residence, drinking, smoking and any substance abuse habits, past obstetric and gynaecological history. Record of each pregnancy in chronological order should include date, place, maturity, labour, delivery, weight, sex and fate of the infant and any puerperal morbidity. If severe give mild laxative and Avoid strong heartburn & Constipation) antacid e. Discourage harmful unusual foods and substances) Give haematinic supplements as for prophylaxis and contaminated materials eg. Patients should be told how to recognize and report promptly any deviation from normal so that prompt treatment may be initiated. Date of first foetal movements • Weight: amount and pattern of weight change • Blood pressure, check for oedema • Urinalysis for glucose, proteins, ketones • Obstetric examination, vaginal examination/speculum as indicated • Repeat laboratory tests, if necessary, e. Principles of management include: − Identification of high risk patient cases − Prophylaxis and prenatal counselling − to prevent some high risk patients − Early start of antenatal care − Close medical supervision during pregnancy − Special tests and examinations to evaluate foetal development and well being as well as maternal well−being − Timely intervention for therapy and delivery. Mild anaemia Hb 8−10 mg, moderate Hb 6−7 gm, severe Hb 4−5 gm, very severe below Hb 4 gm. Most cases are due to Iron deficiency: Dietary deficiency, blood loss from hookworm infestations. Folate deficiency due to inadequate intake especially in urban areas, also due to haemolysis of malaria. Iron deficiency and folk acid deficiency often occur together causing “Dimorphic Anaemia”.

Diseases

  • Anonychia onychodystrophy brachydactyly type B
  • Contractural arachnodactyly
  • Oral squamous cell carcinoma
  • Pseudohypoparathyroidism
  • Acute myeloblastic leukemia type 1
  • Amnesia, retrograde
  • Encephalophathy recurrent of childhood
  • Bronchiolotis obliterans organizing pneumonia (BOOP)
  • Epidermodysplasia verruciformis

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Liver buy 10 mg metoclopramide fast delivery chronic superficial gastritis diet, spleen and adrenal damage may cause severe bleeding and associated hypovolaemic shock metoclopramide 10mg lowest price gastritis diet . K haemorrhage 40−50% of babies below distress buy metoclopramide 10 mg visa gastritis diet vegetables, Convulsions order 10 mg metoclopramide fast delivery gastritis loss of appetite, Fever Conservative 1500 gms. Does not slowly subside but skull bones due to trauma cross midline Bilateral or may become during delivery unilateral infected calcified or lead to jaundice or anaemia. Sternomastoid tumour Tear of sternomastoid Lump on the side of neck Gentle passive muscle during delivery appearing within first two physiotherapy to (especially breech). Long bones Healing takes place so readily that only minimal splinting is necessary, even where there is misalignment. Clinical Features Uniform enlargement of the head before birth causing obstructed labour or developing insidiously after birth. Management − Operative • A shunt from the ventricle to the atrium or peritoneal cavity inserted in a specialised centre. Contraindications to referral (surgery) • Multiple congenital abnormality • Large hydrocephalus associated with spina bifida with paralysis • Severely infected chest, anaemic, blind and vomiting patients. In other cases There may be tell−tale signs on the the patient may present with: back such as: • Nocturnal ehuresis • Lipoma • Foot−drop • Dimple • Persistent urinary tract infections • Tuft of hair (hypertrichosis) • Naevus • Telangiectasia Investigations • X−ray of full spine will show absent lamina on one side or bilaterally • Myelogram may be useful to rule out associated conditions such as diastematomyelia. Management • The patient should be referred a neurosurgeon in a specialised centre. Clinical Features • All cases are obvious as a mass on the back: Many cases are born as still−births • Meningocele and meningo−myelocele can be transilluminated. Contraindications to referral (surgery) • Spina bifida with severe paralysis • Associated severe hydrocephalus or other neural defects • Severe infections (local or systemic). Cleft lip results from abnormal development of the medial nasal and maxillary processes during their development. Timing Operations may be done soon after birth: gives best aesthetic results between 6−12 weeks. This is the optimum timing as other congenital abnormalities have been excluded, baby is showing steady weight and is safe for anaesthesia. Complications Effects on functions • Sucking: Sucking is greatly affected by cleft palate. Cleft palate babies need to be fed by a cup and spoon • Speech: Speech development is impaired • Hearing: Acute and chronic otitis media are common especially in unrepaired cleft palate, due to poor ventilation and drainage of middle ear through the eustachian tubes, deafness may ensue. It must be diagnosed within the first 48 hours of birth Clinical Features • The new born baby regurgitates all its first and every other feed • Saliva drools continuously from the mouth • Attacks of coughing and cyanosis (choking) during feeding • Abdomen distends especially at the epigastrium (due to swallowed air in the stomach). The baby should be transported under the above circumstances to a specialist centre equipped for this type of operation. In some other cases gastrotomy is necessary to allow time for correction on intercurrent conditions. Congenital abnormalities are frequently multiple: a careful general examination of the baby is an important prerequisite. Investigations • It is urgent and important to determine whether the abnormality is high or low. Do an X−ray (Invertogram) 6 hours after birth (air has collected in the large intestine). Low abnormalities These are easy to diagnose, simple to treat and the out look is good. The first treatment is careful dilatation with well lubricated hegar dilators and thereafter digital dilatation. The mother is taught how to dilate the anus • The ectopic anus the anus is situated anteriorly and opens in the perineum in boys or vagina in girls. Refer the baby for this after resuscitation • The covered anus: the treatment is as for stenosed anus • The membranous anus: treatment is a cruciate incision. Management − General • Close co−operation between obstetrician and paediatrician • Maintain normoglycaemia in the mother [see 18. In nursery • Keep baby warm • Monitor: − blood sugar at 1, 2, 3, 6, 9, 12, 24, 48 hrs − calcium levels at 6, 12, 24, 48 hrs − haematocrit at 1 & 24 hrs − bilirubin levels at 24 & 48 hrs • Oral dextrose 10% 60 ml/kg/day to all babies • If hypoglycaemic (blood sugar <2. This is referred to as physiological jaundice and has the following characteristics: • Appears about third day. Reduces to normal in about a week • Peak levels of 10−12 mg/dl (170−205 µmol/L) in preterm babies. Falls to normal about 10 days • Levels >12 mg/dl in term babies and >15 mg/dl (>255 µmol/L) in preterm require investigation. Management • In most cases of physiological jaundice only observation is required. Ensure adequate feeding and hydration 175 • Phototherapy − indications: − babies with rapidly rising bilirubin levels − all jaundiced babies with blood groups or Rhesus incompatibility − term babies with bilirubin level >300 µmol/L (15 mg/dl) − preterm babies with bilirubin level >200 µmol/L (10 mg/dl). Phototherapy is not an alternative to blood exchange transfusion where it is indicated. In their presence exchange transfusion will be required to be done at a lower level: sepsis, prematurity, acidaemia, hypothermia, administration of sulphonamide, hypoglycaemia. Exchange transfusion The exchange transfusion should be carried out over 45 − 60 minutes period alternating aspiration of 20 ml of infant blood and infusion of 20 ml of donor blood. The goal should be an exchange of approximately 2 blood volumes of infant (2x85 ml/Kg). Complication Kemicterus: Brain damage due to deposition of bilirubin in the basal ganglia and brain stem nuclei. Risk of kemictenis is increased in preterm infants with high bilirubin concentrations, low serum albumin concentrations or those on certain drugs such as ceftriaxone and aspirin. Diagnosis Symptoms include lethargy, poor feeding and vomiting, opisthotonos, oculogyric crisis seizures and death may follow. Maternal: Acute febrile illness, malaria, pneumonia, chronic diseases and uterine abnormality. It is characterized by: Tachypnoea, respiration rate more than 60 per minute, expiratory grunt and cyanosis, intercostal, subcostal and sternal recession, flaring of alae nasi. Prevention • Increased and improved pre−natal care • Regular cleaning and decontamination of nursery equipment • Sound hand−washing principles • Regular surveillance for infection. Complications Significant neurological sequelae: Hydrocephalus, blindness, mental retardation, hearing loss, motor disability, abnormal speech patterns. Normal Hb Newborns 14 g/dl Children aged under 5 years 10 g/dl Children aged 5−9 years 11 g/dl Children aged 9 years and above 12 g/dl Anaemia except in the newborn may therefore be classified as follows: • Severe below 5 g/dl • Moderate 5−8 g/dl • Mild above 8 g/dl Common causes of anaemia in Kenya are: • Haemolysis due to infections especially malaria and haemoglobinopathies. Pallor of the mucous membranes (conjunctivae, lips and tongue) nail beds and palms. Investigations • Hb estimation • Thin blood film examination for cell morphology and blood parasites • Stool for ova of helminths, occult blood • Full haemogram • Sickling test/Hb electrophoresis • Bone marrow 184 • Urinalysis. Management • Identify the cause and treat • Malaria: − Give a fall course of an appropriate antimalarial drug. This also replenishes body stores of Iron • Folic Acid: Give to all patients who have malaria and anaemia. Refer If • An infant requires exchange transfusion • You cannot give blood transfusion for any reason • Anaemia is due to persistent or recurrent bleeding which cannot be easily controlled • Anaemia has not improved after one month of supervised treatment (Hb should increase by 2−4 g/dl in one month) • Anaemia recurs within 6 months of full treatment. Admit patients with • Severe anaemia • Active and severe bleeding • Anaemia and/or jaundice and aged below 2 months • The anaemia (any degree of severity) is accompanied by pneumonia, heart failure, dizziness, confusion, oedema, severe malnutrition.

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If you have physical possession of a sample order 10 mg metoclopramide fast delivery diet untuk gastritis akut, have it in view 10 mg metoclopramide otc gastritis snacks, or have it physically secured to prevent tampering order 10 mg metoclopramide visa gastritis in spanish, then it is defined as being in “custody buy cheap metoclopramide 10mg on-line gastritis diet vs exercise. From this point on, a chain of custody record will accompany the sample containers. If you do not seal individual samples, then seal the containers in which the samples are shipped. When the samples transfer possession, both parties involved in the transfer must sign, date and note the time on the chain of custody record. If a shipper refuses to sign, you must seal the samples and chain of custody documents inside a box or cooler with bottle seals or evidence tape. The recipient will then attach the shipping invoices showing the transfer dates and times to the custody sheets. If the samples are split and sent to more than one laboratory, prepare a separate chain of custody record for each sample. If the samples are delivered to after hours night drop-off boxes, the custody record should note such a transfer and be locked with the sealed samples inside sealed boxes. Method 1622 was used to analyze samples from March 1999 to mid-July 1999; Method 1623 was used from mid-July 1999 to February 2000. Alternate procedures are allowed, provided that required quality control tests are performed and all quality control acceptance criteria in this method are met. The equipment and reagents used in these modified versions of the method are noted in Sections 6 and 7 of the method; the procedures for using these equipment and reagent options are available from the manufacturers. Waterborne Diseases ©6/1/2018 353 (866) 557-1746 Because this is a performance-based method, other alternative components not listed in the method may be available for evaluation and use by the laboratory. Confirming the acceptable performance of the modified version of the method using alternate components in a single laboratory does not require an interlaboratory validation study be conducted. However, method modifications validated only in a single laboratory have not undergone sufficient testing to merit inclusion in the method. Only those modified versions of the method that have been demonstrated as equivalent at multiple laboratories and multiple water sources through a Tier 2 interlaboratory study will be cited in the method. This Cryptosporidium-only method was validated through an interlaboratory study in August 1998, and was revised as a final, valid method for detecting Cryptosporidium in water in January 1999. The method has been validated in surface water, but may be used in other waters, provided the laboratory demonstrates that the method’s performance acceptance criteria are met. The panel was charged with recommending an improved protocol for recovery and detection of protozoa that could be tested and implemented with minimal additional research. The magnetized oocysts and cysts are separated from the extraneous materials using a magnet, and the extraneous materials are discarded. Oocysts and cysts are identified when the size, shape, color, and morphology agree with specified criteria and examples in a photographic library. In addition to naturally-occurring debris, such as clays and algae, chemicals, such as iron and alum coagulants and polymers, may be added to finished waters during the treatment process, which may result in additional interference. All materials used shall be demonstrated to be free from interferences under the conditions of analysis by running a method blank (negative control sample) initially and a minimum of every week or after changes in source of reagent water. Specific selection of reagents and purification of solvents and other materials may be required. Experience suggests that high levels of algae, bacteria, and other protozoa can interfere in the identification of oocysts and cysts (Reference 20. This method does not purport to address all of the safety problems associated with its use. It is the responsibility of the laboratory to establish appropriate safety and health practices prior to use of this method. In particular, laboratory staff must know and observe the safety procedures required in a microbiology laboratory that handles pathogenic organisms while preparing, using, and disposing of sample concentrates, reagents and materials, and while operating sterilization equipment. The laboratory is responsible for maintaining a current awareness file of Occupational Safety and Health Administration regulations regarding the safe handling of the chemicals specified in this method. A reference file of material safety data sheets should be made available to all personnel involved in these analyses. Reference materials and standards containing oocysts and cysts must also be handled with gloves and laboratory staff must never place gloves in or near the face after exposure to solutions known or suspected to contain oocysts and cysts. Gloves must be removed or changed before touching any other laboratory surfaces or equipment. Unless the sample is known or suspected to contain Cryptosporidium, Giardia, or other infectious agents (e. Equivalent performance may be achieved using apparatus and materials other than those specified here, but demonstration of equivalent performance that meets the requirements of this method is the responsibility of the laboratory. Other options may be used if their acceptability is demonstrated according to the procedures outlined in Section 9. The version of the method using this filter was validated using 10-L sample volumes; alternate sample volumes may be used, provided the laboratory demonstrates acceptable performance on initial and ongoing spiked reagent water and source water samples (Section 9. The version of the method using this filter was validated using 10-L sample volumes; alternate sample volumes may be used, provided the laboratory demonstrates acceptable performance on initial and ongoing spiked reagent water and matrix samples (Section 9. The version of the method using this filter was validated using 50-L sample volumes; alternate sample volumes may be used, provided the laboratory demonstrates acceptable performance on initial and ongoing spiked reagent water and matrix samples (Section 9. At a minimum confirm that the test filter expands properly in water before using the batch or shipping filters to the field. Before use, the tubing must be autoclaved, thoroughly rinsed with detergent solution, followed by repeated rinsing with reagent water to minimize sample contamination. Alternately, decontaminate using hypochlorite solution, sodium thiosulfate, and multiple reagent water rinses; dispose of tubing when wear is evident. Weigh 10 g of Laureth-12 and dissolve using a microwave or hot plate in 90 mL of reagent water. Dispense 10-mL aliquots into sterile vials and store at room temperature for up to 2 months, or in the freezer for up to a year. Rinse the vial several times to ensure the transfer of the detergent to the cylinder. Store reagents o o at 0 C to 8 C and return promptly to this temperature after each use. However, the laboratory is not required to analyze additional ongoing precision and recovery samples or method blank samples for each type. Chill samples as much as possible between collection and shipment by storing in a refrigerator or pre-icing the sample in a cooler. If the sample is pre-iced before shipping, replace with fresh ice immediately before o o shipment. Samples should be shipped at 0 C to 8 C, unless the time required to chill o the sample to 8 C would prevent the sample from being shipped overnight for receipt at the laboratory the day after collection. Upon receipt, the laboratory should record the temperature of the samples and store them o o refrigerated at 0 C to 8 C until processed.

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Photosensitivity was mainly a prob- lem with older purchase metoclopramide 10mg with visa gastritis symptoms lump in throat, now no longer used 10mg metoclopramide sale gastritis fasting, analogues order 10 mg metoclopramide overnight delivery chronic gastritis/lymphoid hyperplasia. Minocycline can cause a dark-brown pigmentation of the skin or acne scars or acral areas on the exposed part of the skin after long- continued use in a small number of patients discount metoclopramide 10mg online gastritis diet . Tetracyclines must not be given to pregnant women, as they are teratogenic, and must not be given to infants, as they cause a bone and tooth dystrophy in which these structures become deformed and discoloured. Erythromycin The efficacy of erythromycin in acne is similar to that of the tetracyclines. The starting dosage is 250 mg 6-hourly for the first few weeks, with reduction after a response has begun. Other antibiotics and antimicrobials Clindamycin, the quinolines and the sulphonamides are other drugs that have been used systemically for acne. None is more effective than the tetracyclines, but they may be suitable for patients who are either intolerant or who no longer respond to the tetracyclines or erythromycin. Isotretinoin (13-cis-retinoic acid) The large majority of patients with acne will respond to topical or some combin- ation of topical and systemic drugs. However, some severely affected patients may not, and for them there is another drug that can offer relief. This agent is the retinoid isotretinoin (the same cis-isomer of tretinoin used topically). It reduces sebum secretion by shrinking the sebaceous glands and may also alter keratiniza- tion of the mouth of the hair follicle and have an anti-inflammatory action. The response after a few weeks is to inhibit new lesions in more than 80 per cent of patients. Patients with many large cystic lesions affecting the trunk as well as the head and neck region take longer to respond and may need more than one 4-month course. They range from the trivial, of which the most common is drying and cracking of the lips, to the very serious, which include teratogenicity, hepatotoxicity, bone toxicity and a blood lipid- elevating effect. The teratogenic effects are very worrisome, as the acne age group is almost identical to the reproductive age group. The effects on the fetus include facial, cardiac, renal and neural defects and are most likely to arise if the drug is taken during the first trimester. Some 30–50 per cent of pregnancies during which the drug was taken have been affected. Because of this, it is strongly recommended that if it is planned to prescribe isotretinoin for women who can conceive, effect- ive contraceptive measures must also be planned and used during and for 2 months after stopping the drug. A rise in triglycerides and cholesterol, such that the ratio of very low-density lipopro- teins to high-density lipoproteins is increased, regularly occurs, and overall there is a 30 per cent rise in lipid levels. This is not likely to be a problem for most patients with acne, but may be for older patients. A variety of bone anomalies have been described, including disseminated interstitial skeletal hyperostosis and osteoporosis, but these are not likely to be a problem for acne subjects. The drug has also been accused of causing severe depression, leading to suicide in some cases. The evidence for this is not strong, as severe acne patients are often depressed before starting treatment. New spots appeared every day and she spent hours in front of the mirror trying to squeeze out blackheads and get rid of pustules. It made her quite depressed and matters were made worse by her parents telling her that she didn’t wash her face enough and that going to discos didn’t help her skin. Anti-androgens Anti-androgens inhibit androgenic activity and reduce sebum secretion. This is a mixture of an anti-androgen, cyproterone acetate (2 mg), and an oestrogen, ethinyl oestradiol (35 g). It is a central anti-androgen, blocking the pituitary drive to androgen secre- tion. It improves acne after some 6–8 weeks of use, but is not as effective as isotretinoin. It is associated with a number of minor side effects, essentially those associated with taking oral contraceptives. Spironolactone, the potassium-sparing diuretic, has also been found to have anti-androgenic effects and has occasionally been used as a treatment for acne. Sometimes only one or two areas are affected, and this makes diagnosis quite difficult. The lesions The most characteristic physical sign is that of persistent erythema, often accom- panied by marked telangiectasia (Fig. Superimposed on this persistent background of erythema are episodes of swelling and papules, which develop for no very obvious reason (Fig. The papules are a dull red, dome shaped and non-tender, in contrast to acne, in which they tend to be irregular and tender. Pustules also occur, but are less frequent than in acne; blackheads, cysts and scars do not. Acne occurs in a younger age group and is usually distinguished by the greasy skin, comedones and scars as well as lesions on sites other than the face. However, in some patients, the presence of persistent erythema can make differentiation quite difficult. Perioral dermatitis (see page 168) should not be difficult to differentiate, as this disease is mainly distributed around the mouth and there is no background of erythema. Systemic lupus erythematosus may superficially resemble rosacea, become of the symmertrical butterfly erythema but there are no symptoms of systemic disease in rosacea. Dermatitis of the face (including seborrhoeic dermatitis) is marked by scaling, which is not characteristic of rosacea. The car- cinoid syndrome is characterized by reddened areas on the face in the same 163 Acne, rosacea and similar disorders Table 10. Dermatomyositis is characterized by mauvish erythema around the eyes, but the pain, tenderness and weakness of limb girdle muscles should quickly distin- guish this disease. The nose becomes irregularly enlarged and ‘craggy’, with accentuation of the pilo- sebaceous orifices (Fig. At the same time, the nose develops a mauve or dull-red discoloration with prominent telangiectatic vessels coursing over it (Fig. Popular names for this include ‘whisky-drinkers nose’ and ‘grog blossom’, but it is not due to alcoholism. Lymphoedema Persistent lymphoedema is another unpleasant, though uncommon, complication of rosacea seen predominantly in men. The swollen areas are usually a shade of red and may persist when the other manifestations of rosacea have remitted. Ocular complications Some 30–50 per cent of patients with acute papular rosacea have a blepharocon- junctivitis. This is usually mild, but some patients complain bitterly of soreness and 164 Rosacea Figure 10.

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